Atlético Madrid take on Osasuna in one of 10 midweek La Liga fixtures. Diego Simeone’s side need three points at the Estadio Metropolitano to avoid losing further ground on the top two.

Atlético Madrid hoping David can be the answer in attack

With the derby against Real Madrid to come this Sunday, Simeone will consider some light rotation. However, he is still short on options up front, given Julián Álvarez and Alexander Sørloth are both injury doubts.

Recent signing Jonathan David did come on to score in the 3-0 win at Real Sociedad on Sunday. The Canadian scored three times in five appearances at the 2026 World Cup and could make his first start for Atleti in this match.

Midfielder Pablo Barrios picked up an injury last week, and he’s set to miss this game as a result. Koke and Morten Hjulmand are therefore likely to team up in the centre of the pitch.

Atlético Madrid predicted lineup vs Osasuna (3-4-2-1): Oblak; Romero, Pubill, Hancko; Simeone, Hjulmand, Koke, Grimaldo; Baena, Lookman; David.

Budimir still leading the way for Osasuna

It is a familiar story for Osasuna, with much of their goal threat again coming from Ante Budimir. The Croatian has netted 17 or more times in each of his previous three seasons in La Liga and is already on four goals in five appearances this term.

Luis Miguel Ramis is looking for solutions following back-to-back defeats. The recently appointed coach is hampered by injuries to Jorge Herrando, Moi Gómez and Aimar Oroz. He also has a fitness doubt over Valentin Rosier.

Alejandro Catena is the key figure at the back. The centre-back is averaging 1.4 tackles and 5.6 clearances per game for Los Rojillos in La Liga 2026/27.

Osasuna predicted lineup vs Atlético Madrid (4-2-3-1): Herrera; Arguibide, Boyomo, Catena, Bretones; Moncayola, I. Muñoz; Del Castillo, Rubén García, Moro; Budimir.

Atlético Madrid vs Osasuna Prediction

  • Safe Tip: Atlético Madrid to win
  • Odds: 1.49 (22Bet)
  • Correct score prediction: Atlético Madrid 2-0 Osasuna
  • 22Bet Booking Code: FAAKS

Key stats:

  • Atlético Madrid have won three of their opening five league fixtures.
  • Simeone’s team have triumphed in five of their last six meetings with Osasuna at the Estadio Metropolitano.
  • Osasuna have conceded seven times across their last two outings, losing on each occasion.

It was an unconvincing start to the campaign from Atleti, but their World Cup stars are now back to full fitness, while David has emerged as useful cover up front. They’ve won three of their past four clashes with Osasuna in La Liga and backing a home win is a safe pick here.

Los Rojiblancos won 79% of their league fixtures at the Estadio Metropolitano last term. Their opponents conceded five in their most recent away fixture against Alavés, while they remain dependent on Budimir for goals. Only one other Osasuna player has scored this season.

Atlético Madrid vs Osasuna Prediction, Value Tip

  • Value Tip: Álex Baena to score a goal including substitutions
  • Odds: 3.09 (22Bet)
  • 22Bet Booking Code: JZEKS

At odds of 3.09, Álex Baena offers value to score a goal, including substitutions. He is operating in an advanced role, which ensures he gets into plenty of dangerous positions.

The Spain international has already netted three times in five league outings this term. He’s averaging 1.8 shots per game.

Verdict: Atlético Madrid to win (1.49) — Atlético Madrid 2-0 Osasuna