PSV Eindhoven and Shakhtar Donetsk will both be targeting a top-24 finish in the Champions League. A victory for either side at the Philips Stadium would be a major step in the right direction.

PSV hit by selection issues

It was a busy finish to the summer at PSV Eindhoven. They completed a couple of transfers towards the end of the window, with Sam Lammers joining from Twente, while Sami Ouaissa arrived from NEC. Both players will bolster Peter Bosz’s attacking options, although Ouaissa is currently injured.

The forward line is unlikely to change here, following an excellent 3-1 win at Ajax on Saturday. Striker Ricardo Pepi scored in that game to move onto three goals in five outings so far this term.

PSV will need to cope without the suspended Mauro Júnior. Dennis Man, Kilian Sildillia, Jerdy Schouten and Alassane Pléa are additional injury absentees.

PSV Eindhoven predicted lineup vs Shakhtar Donetsk (4-3-3): Kovář; Dest, Geertruida, Obispo, Kostić; Sano, Til, Fernandez; Perišić, Pepi, van Bommel.

Alisson the danger man for Shakhtar Donetsk

There was some light rotation from Shakhtar Donetsk when they won 2-1 away to Karpaty Lviv in the Ukrainian Premier League on Saturday. Arda Turan will recall both Kauã Elias and Vinícius Tobias for this European fixture.

The visitors are doing better on the selection front than their opponents, but could still be without three players. Goalkeeper Kiril Fesiun is unwell, while Pedrinho and Marlon Santos are likely to miss out through injuries.

Alisson has been the standout player for Shakhtar so far this season. The 20-year-old is an exciting prospect on the right flank, with two goals and two assists in his opening five appearances.

Shakhtar Donetsk predicted lineup vs PSV Eindhoven (4-3-3): Riznyk; Vinícius Tobias, Bondar, Matviyenko, Henrique; Nazaryna, Ocheretko, Gomes; Alisson, Elias, Newerton.

PSV Eindhoven vs Shakhtar Donetsk Prediction

  • Safe Tip: Both teams to score
  • Odds: 1.59 (22Bet)
  • Correct score prediction: PSV Eindhoven 3-1 Shakhtar Donetsk
  • 22Bet Booking Code: Y8CH3

Key stats:

  • There were five goals and 47 shots when these clubs last met in the Champions League in 2024.
  • Both teams have scored in each of the past five PSV Eindhoven matches.
  • Shakhtar Donetsk are averaging two goals per game in the 2026/27 season.

Even in tougher fixtures, PSV Eindhoven look to take risks and chase goals, which is sure to be the case in a match they are clear favourites to win. They are scoring freely, with 14 goals across their last three games. However, the Dutch side are yet to keep a clean sheet in six outings this term.

With Brazilians Alisson and Newerton on the flanks, Shakhtar should ask questions on the break. All of their previous three European fixtures have seen both teams score. Backing that to be the case again is a safe pick on Thursday.

PSV Eindhoven vs Shakhtar Donetsk Prediction, Value Tip

  • Value Tip: PSV Eindhoven to score over 2.5 goals
  • Odds: 2.18 (22Bet)
  • 22Bet Booking Code: HPFH3

With an average of 3.6 goals per game, PSV Eindhoven are the top scorers in the Eredivisie. They also netted 16 times across their eight matches in the league stage of the 2025/26 Champions League.

In a favourable home fixture, backing Bosz’s side to score over 2.5 goals offers value at odds of 2.18.

Verdict: Both teams to score (1.59) — PSV Eindhoven 3-1 Shakhtar Donetsk