Como kick off their first-ever Champions League campaign on September 10 when they host RB Leipzig at Stadio Giuseppe Sinigaglia.

Como Chasing Historic Win

This season, Cesc Fabregas will guide Como 1907 into their first-ever Champions League campaign. The Italian side have made an excellent start to 2026-27, avoiding defeat in three and winning back-to-back fixtures.

Their offensive strength has impressed in their last two, scoring six goals. Assane Diao has been a star performer for I Lariani, registering three goal involvements in two appearances. Martin Baturina has also found the net in back-to-back clashes.

Fabregas will be without Dutch winger Jayden Addai on Thursday, but Robert Sanchez will be in line for a first start after signing from Chelsea.

Como predicted lineup vs RB Leipzig (4-2-3-1): Sanchez; Couto, Ramon, Chalobah, Valle; Da Cunha, Perrone; Diao, Paz, Baturina; Douvikas

Leipzig Impressing In Final Third

Martín Demichelis has enjoyed a strong start to his RB Leipzig reign, having won two of his last three fixtures. Leipzig will need a response after a recent Bundesliga defeat to Werder Bremen, meaning they have now allowed five goals in their last four.

Their attacking strength should be respected, as the German club have scored ten goals in their previous three encounters.

Tidiam Gomis has been an eye-catching performer in recent weeks, recording three goal involvements in as many appearances. Demichelis will be without a couple of first-team stars this week, including Castello Lukeba, Rocco Reitz, and Assan Ouedraogo.

RB Leipzig predicted lineup vs Como (4-3-3): Vandevoordt; Baku, Orban, Esteve, Raum; El Aynaoui, Seiwald, Banzuzi; Gruda, Gomis, Nusa

Como vs RB Leipzig Prediction

  • Safe Tip: Both Teams to Score
  • Odds: 1.52 (22Bet)
  • 22Bet Booking Code: D7VM3
  • Correct score prediction: Como 3-2 RB Leipzig

Key stats:

  • Como have scored and conceded in each of their last three fixtures.
  • RB Leipzig have conceded at least once in two of their previous four.
  • Leipzig have netted at least once in five of their six games.

An entertaining first taste of Champions League football is to be expected at Como on Thursday, and BTTS looks like a standout selection. The Italian club have excelled this term offensively, scoring seven goals in their last three fixtures, but they have also failed to keep a clean sheet in their previous six.

RB Leipzig’s attacking threat has seen them register at least one goal in five of their most recent six, but they have also allowed at least one effort in half of their four encounters.

Como vs RB Leipzig Prediction, Value Tip

  • Value Tip: Nicolas Paz to Score
  • Odds: 2.8 (22Bet)
  • 22Bet Booking Code: 3GE53

Nicolas Paz is a standout value choice to score at 2.8 this week. The attacking midfielder registered 20 goal involvements for Como last season, and he was clinical in front of goal, with a shot accuracy of 40%.

Paz has already shown his importance to the team in the final third this season with a goal against Genoa, and he could be a key threat from a deeper role on Thursday.

Verdict: Both Teams to Score (1.52) — Como 3-2 RB Leipzig