Ghana will be chasing an immediate return to form when they play their second match in Africa Cup of Nations qualification on September 29, when they host Gambia.

Ghana Stuttering for Form Under Queiroz

Carlos Queiroz will be hoping for a response from his Ghana team this week following an underwhelming opening to AFCON qualification after losing against the Ivory Coast.

Ghana have now suffered defeats in three straight internationals, and they have won just once in nine matches in 2026.

Antoine Semenyo and Mohammed Kudus are out. Ibrahim Sulemana could return to the starting eleven this week after being rested last week. Ernest Nuamah could lead the line after scoring three goals in four matches for Lyon in 2026-27.

Ghana predicted lineup vs Gambia (4-2-3-1): Ati-Zigi; Yeboah, Adjetey, Mensah, Opoku; Sulemana, Yirenkyi; Fatawu, Thomas-Asante, Baah. Nuamah

Gambia Chasing Successive Qualifying Wins

Johnny McKinstry would have been delighted with Gambia’s start to AFCON qualifying following a 2-1 home win against Somalia.

Gambia have now avoided defeat in three of their last five, and their recent win was an excellent return to form following back-to-back defeats. However, defensive improvement will still be required, as Gambia have allowed at least two goals in three of their previous four.

They have also kept just one clean sheet in their six most recent internationals. Ebrima Colley will be a key player in the final third after racking up three goal involvements in his last seven starts.

Gambia predicted lineup vs Ghana (4-2-3-1): Gaye; O. Colley, Gomez, Sanyang, Touray; Adams, Drammeh; Fadera, Badamosi, E. Colley; Ceesay

Ghana vs Gambia Prediction

  • Safe Tip: Ghana
  • Odds: 1.49 (22Bet)
  • 22Bet Booking Code: CY3F6
  • Correct score prediction: Ghana 2-1 Gambia

Key stats:

  • Ghana have won back-to-back internationals against Gambia since 2017.
  • They are unbeaten in their last three home fixtures.
  • Gambia have lost three of their previous six internationals.

This should be a good opportunity for Ghana to bounce back to winning form. They have been reliable in home matches since the start of last year, having avoided defeat in their previous three.

Ghana have also avoided defeat in half of their previous six, which includes a notable draw over highly-ranked England. Gambia have been underwhelming against better nations, losing three of their last six. Meanwhile, Ghana have won consecutive head-to-heads against the rivals since 2017.

Ghana vs Gambia Prediction, Value Tip

  • Value Tip: Both Teams to Score
  • Odds: 2.15 (22Bet)
  • 22Bet Booking Code: UD5F6

Both Teams to Score (BTTS) could be an interesting value angle this week. Gambia have scored at least once in their previous nine internationals, which includes goals in losing efforts against high-ranked teams such as Senegal and Iran earlier in 2026.

Ghana’s defensive record should also ensure that the visitors get chances this week, as the hosts have failed to keep clean sheets in seven of their last nine. Meanwhile, BTTS has been a winning selection in four of their nine matches in 2026.

Verdict: Ghana (1.49) — Ghana 2-1 Gambia