Both Cagliari and Internazionale opened the 2026-27 Serie A season with a win, and the goal is to maintain their perfect start to the campaign when these two sides lock horns on Sunday at Unipol Domus.
Cagliari aiming to pull a huge upset at home
Cagliari have enjoyed a strong start to the 2026-27 season after notching back-to-back 1-0 victories over Arezzo in the Coppa Italia on August 14 and Parma in the 2026-27 Serie A opener on August 22. However, they’ll need to deliver an improved performance if they’re going to pull off the upset at home against Internazionale.
This has been a tough opponent for Cagliari over the years. Rossoblù have taken just one point of the last 30 available against Internazionale in league play (D1, L9) and haven’t defeated them since March 2019.
With those numbers, and after a mere 0.94 xG in the win over Parma, it’s clear the hosts have some work to do if they’re going to pull the upset in front of their fans.
Cagliari predicted lineup vs Internazionale (4-2-3-1): Capriile; Ze Pedro, Mina, Rodriguez, Obert; Romano, Winks; Adopo, Fazzini, Maldini; Mendy
Can Inter Milan handle being the odds-on favourite?
Any result that’s not a win for Internazionale should be a huge shock. There’s a gulf in talent, experience, and depth between these two sides, and seemingly every angle in which this game is analysed favours Internazionale one way or the other.
Cristian Chivu’s men still need a few signings to round out the squad, could use another goalkeeper, and have yet to see Djed Spence make his debut. But even if they repeat the same squad from their win over Monza, they should be considered the better team.
With a clear edge in the head-to-head record and the edge of six straight away competitive matches undefeated (W3, D3), the Nerazzurri are clear favourites.
Internazionale predicted lineup vs Cagliari (3-5-2): Josip Martínez; Bisseck, Bastoni, Akanji; Diouf, Zielinski, Barella, Calhanoglu, Dimarco; Esposito, Lautaro Martínez
Cagliari vs Internazionale Prediction
- Safe Tip: Inter Milan to win
- Odds: 1.42 (22Bet)
- Correct score prediction: Cagliari 0-2 Inter Milan
- 22Bet Booking Code: Z7M1J
Key stats:
- Internazionale have won their last four H2H against Cagliari.
- They haven’t lost away from their fans since March 8.
- Rossoblù haven’t defeated Internazionale at home since the 2018-19 season.
Internazionale are the better team on paper, and the head-to-head record also paints an impressive picture. Nerazzurri haven’t lost against Cagliari in 13 matches overall (W11, D3), with the last defeat coming at this venue in March 2019. They’ve also won the last four head-to-head, scoring 11 times and conceding once.
Squad strength aside, Internazionale are the reigning league champions and kicked off the season with a convincing 4-1 win over Monza, whereas Cagliari secured a 1-0 win over Parma with an xG under 1.00 (0.94). That kind of offensive output shouldn’t threaten the visitors.
Cagliari vs Internazionale Prediction, Value Tip
- Value Tip: Both teams not to score
- Odds: 1.66 (22Bet)
- 22Bet Booking Code: 7761J
Internazionale conceded once against Monza in the season opener. Still, they’ve had excellent results when facing Cagliari, keeping a clean sheet in three of the last four head-to-head meetings, including the two in 2025-26.
Knowing Nerazzurri must tighten things up defensively after allowing Monza to post a 1.23 xG, they should take advantage of Cagliari’s lack of attacking power. Rossoblù have also suffered against Internazionale, failing to score in four of the last six head-to-heads.
Verdict: Internazionale to win (1.42) — Cagliari 0-2 Internazionale.
