Big-spending Tottenham Hotspur kick off their 2026-27 Premier League campaign at the Gtech Community Stadium against Brentford on August 22.

Brentford Aiming to Build on European Near-Miss

Keith Andrews defied all expectations last term to guide Brentford to the cusp of European qualification for the first time in their history.

A new season brings with it new challenges, and the Bees have lost the influential Jordan Henderson to Chelsea. However, major money has been spent replacing the England international, with Malian Mamadou Sangare offering more physicality in the middle of the field.

Jaidon Anthony will provide a direct threat from wide after registering ten goal involvements for Burnley last term. First-team central defender Sepp van den Berg is unavailable due to injury this weekend, while Benjamin Fredrick has also been ruled out.

Brentford predicted lineup vs Tottenham Hotspur (4-2-3-1): Kelleher; Kayode, Pinnock, Collins, Henry; Sangare, Janelt; Schade, Damsgaard, Lewis-Potter; Thiago

Spurs Set Sights High After Major Investment

Roberto De Zerbi begins his first full term in charge of Tottenham with hopes that relegation battles are a thing of the club’s past.

De Zerbi has been heavily supported by the board this summer, with over £200 million spent bringing in Sandro Tonali and Matheus Fernandes. The central defensive positions have also been bolstered with Jan Paul van Hecke and Marcos Senesi. Both will compensate for the departure of Cristian Romero.

Fit-again James Maddison will be crucial in attacking areas, while Richarlison has scored three times in four pre-season appearances. De Zerbi will be without Mohammed Kudus, Xavi Simons, and Dejan Kulusevski on the opening weekend.

Tottenham Hotspur predicted lineup vs Brentford (4-2-3-1): Kinsky; Porro, van Hecke, Van de Ven, Robertson; Tonali, Bergvall; Gallagher, Fernandes, Tel; Richarlison

Brentford vs Tottenham Hotspur Prediction

  • Safe Tip: Under 3.5 Goals
  • Odds: 1.44 (22Bet)
  • 22Bet Booking Code: EPD9U
  • Correct score prediction: Brentford 0-2 Tottenham

Key stats:

  • Under 3.5 goals have been scored in each of the last three head-to-head meetings.
  • Tottenham have improved defensively during pre-season, allowing just five goals in seven fixtures.
  • Brentford have failed to score in three straight games against Spurs.

A low-scoring clash to kick off the campaign is set for Saturday, ensuring that there is appeal in under 3.5 goals.

No more than two goals have found the net in each of the last three head-to-head encounters between Tottenham and Brentford, with the Bees unable to score in all fixtures over that period.

Spurs have also improved defensively after the additions of Andrew Robertson, Senesi, and van Hecke, keeping clean sheets in three of their last seven matches.

Brentford vs Tottenham Hotspur Prediction, Value Tip

  • Value Tip: Tottenham Hotspur to Win
  • Odds: 2.736 (22Bet)
  • 22Bet Booking Code: 2J39U

A fast start to the campaign will be expected by De Zerbi after Tottenham have battled against relegation for the last two terms. Spurs have been excellent throughout pre-season, going seven without defeat and picking up notable wins against Chelsea and Hoffenheim.

Tottenham also dominate the head-to-head record against the Bees, winning two of their previous three, and claiming victories in five of the ten EPL clashes between these sides.

Verdict: Under 3.5 Goals (1.44) — Brentford 0-2 Tottenham Hotspur